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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1983e28c8cfbc5777bb0acc322c2bcc4a05b67ea941e38316b5bfd0ba068c1' 
  AND token = 'GYVbdfh+o5+vHaX9u0kcF69Lo4CnMiaDMo3GZ0WzQYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}