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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28f7ea407d86278742033c9e42fca0977e2be2ff578041a2895d960657c184a' 
  AND token = 'TFluJxCOk3XOOCa5NWbKkXXFnTA9cVFK8+KCcRbZYS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}