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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ce6e2d5ea27979194c00b144cc76444d000d8e6c7eee555bb0c570e402dd8f' 
  AND token = 'o6QW4OWCE9d11w2GWGginVBuIz47dMCDHZXRzqP1RGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}