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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bb6f4abb5751897e5cf05ffeb1d4e85cbfdc63e42c4b5ef45c6d7ee3454b3c' 
  AND token = 'Y0QXNcfQy+D6YGVf1IFt+/wnhP89Q1wARIv/QKixyNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}