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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '700736dc729d26683f6a03eb3e817a333d7cd5787568747588e0816137c1c4ac' 
  AND token = 'DoSLCoA09oFMW+yfOAQPsrUZZRyf/48tWojq8/ZYt2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}