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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878dbb48c7f00011b5f2d460d89026b94727df3e152c3b985f3d3cb44b81995d' 
  AND token = 'r3z5W99bOg8NUcZ/qf3p9JKqtC99JNsmzhqX7bzeZV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}