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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec97dde4caaa372425529792dc7ee37c594d70bb7c943a5d4b70fc37e7f26e20' 
  AND token = 'FdkIH9Yp1v3/MCL0iU1R90dYR8YWoiNQIZW0m+OtPNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}