SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e3ef5c1589494000af21bf9f51a5504f203830ad34cc8e93c90bb4009b734d5' 
  AND token = 'onxOXB31HcZGSwZ9+UcJSqX7mYsr8tphdYpAnSpD5Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}