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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba2c4e837e77a7d40f0b69f451087efc582b19769eb853ed8b17a866b881a43' 
  AND token = '6iHYculi8twjk1R/KVZDYb3wAKKqu0vjwHfl7WulYwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}