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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd92a8dd7cdc318e1b347e82517a3515497c717ca726892ad6a4d9c0107148cd8' 
  AND token = 'JdLZp4SV3YxPVfEDs6+h8x4IFO63cgdyPlZUJSeKNRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}