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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '540e6b68aeb902587922e2dfd06dba7f9156a32473ffc5e402bc10da571b38f3' 
  AND token = 'CRC2DGrdYDYojKq4umeHWpdz27QA36zlPzRGxSO6IGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}