SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52382ea7355516038f2dfd63fefeb7f46eb7274cb093286399f00993e0590104' 
  AND token = 'JTrRno45dMNjwrs4igHG4NQSS8NItb/04o1Y0URouzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}