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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38a29ff670d6b5936f3aebd6cd3e7bc106cb4444343d2fb8640e4d420009ea5' 
  AND token = 'FowjbVM4KPBBH5dUpT3yd8/Os5c4q/fLOz6yrKO+E18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}