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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e3f36135082ae1af20c9b1067d3aa75245aff310f766393564dc6effe2aa34' 
  AND token = 'e8sHRvFpas3pyoBy34yqstUA1CyXJZhSxSOk9+hLmOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}