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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca800eadeb028e495063f77a49c6b0c799259f83f921c8cee52de809d60c43a' 
  AND token = 'rxCKG61LDlvDPZ8aTwtixinwqBQSmprRi+F2i220wpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}