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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c85825fff7225232dd07dbae0451c9afcc839fd0955f6d639ed1d51c68bbe03' 
  AND token = 'Ds0Ovr55hDVIP1s4VKaYb6M5egN/Qqh9BL6QvW4L4FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}