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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f2ac6ce3377a653f3afb702da8aa7d924aa6c79ce74174a7838c8d674e4af0' 
  AND token = 'BSRNQS3S5miVrBjoRhBPZj5s5F06fpln5rQqP5WddKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}