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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5120f9322472758bae92519e197780e696a5e29d9f02c190566012f989072883' 
  AND token = 'is+lC3j3ZA5s9vEaOxSac8XcqtN02QAPsSnGmZ8VAqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}