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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7778e39b9e070407955441078a20139c3a353beee32c65a6dde89d58feb7bd1f' 
  AND token = 'EL+Wqqx25E7z3++8kpPrdV4/Dm1pW1pLdhdK1nofglo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}