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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8157b595ca451debfc0d1dcf6ed976825000d5d9404b4195345220badb8f51e0' 
  AND token = 'InLagmI2pgLVKkR+GcuWVSMSuZfaJ+Uz/5oARKeQ4mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}