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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f94f91366fb705461468dc9a749a42607b9c9b0b88bb30cd5cab3b2121c752' 
  AND token = 'e6FqbtcNH41m5lLDI+DNAeRWUCP9bcjY2IXiocx3G8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}