SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9954e3dc3654c093a79ff2b769da3e677a3b43413391d59da15698c3d3571323' 
  AND token = 'E5NFJ8ic6uSczcmT9uDPFtYOyfiMhWr7gOuSSywg3EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}