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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdc417de1f9fc1aa21bf17f1291eaa448225a522610e3f272b118e3f78f2780a' 
  AND token = 'GaB7hR/pC76MqXpjAO4wY4gvk5vuCQGryBh8CbuQr+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}