SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53498be6fdb6c0d56d4b1f355cff11b6cafe4b0a1677421f1ec868054bdd90c' 
  AND token = 'yNRvjBIYEQdK8ctFDAVoWc4ASIpVJL3WxGn8IFHjx4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}