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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba11309a96765fa0c2620b58b22b4bbad1921eb73454ae7fc5dd6a66a4e30e9' 
  AND token = '0/N/c9bB+1qan/HhV4gMQzcAd0zk1tRIXL01ocjTi58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}