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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2f3b376e3b0b4852d760f139d3202a0d835bb84e76c2c0816c40af5d27c3b5' 
  AND token = 'aK+DfPGrYLyZJIesmCEKZfmPEtqtk8TMGGCwrX+IECk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}