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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5301998ea0abffa124d9f430fefdcc685800cca4c10287454a04c5f4ad6d46' 
  AND token = '2qZ7dK4Np/ZJQ9y0uOPOi+WuTSWxi5RryaFNk42lzmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}