SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0053b2da90a5d32e58078038a85e8f43c985c8d02ff3b1d786bcef033f31c246' 
  AND token = '00p2noU+mnB5EN06PJL/sHxeTJmPQ197DbmUOOSuC7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}