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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9048eec91c00db5c9f44552db49c10f5bb48c5cb35bb22db069865a596e66bd' 
  AND token = '/Nq0oxiciO0H8kCE5Oy/5XEHw2AVbBfTjsSd+KqQUzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}