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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b566cbdf4eba6ab89b636b22c15ee8cb4b52d05b71c7ddeda752d9c296d4a460' 
  AND token = 'tZU5h4Uc6DkaM+thUO2wIb5Vl5L1lotMRynNJKSwFlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}