SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bad99901319ef253a64abdc87929d37132f58dd521c77f0eaa4929f59e3eae' 
  AND token = '4LcTFOT+5JoVf/3xpLr8dU365U0EC+gsdrUdy3lnTPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}