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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2726b19db7f33ccc5e39079267b48a4fd7325a44bdf5464e024c078c510b6a' 
  AND token = 'OSns0a18ivB8DS4JNin/u3eQh7WoxNWzVRSRVocw4es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}