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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9900bde337bdd77afd9ec3b0df1d384bdf73fa8c1fc7274c552d1696dbbd0d65' 
  AND token = 'ZN6aDd8JrXQ48AkfLdZDdhWuKets+TOrL/ZP1KOeyCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}