SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a060c01bf983a69bbfd76d52713f233d4332583ad7efe5fc9ed188fe942811' 
  AND token = 'fToaMc0Wg8DR0RN6HFmZWvWFs0yWYm6sLpuB6PfLJIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}