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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca39568ab1fdc02c7644e2124ac789f4440a84f3504863459692b557f1d1b6b4' 
  AND token = 'jH0pgNE2CCW+rgnFzZCdg9Az0wwCbvusSSKyI22sIW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}