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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b36cade306c6a6638a54a4d5a105892110f75c388587ccfb01414c8758f2ea1' 
  AND token = 'SLqv+q1xEEIAURCJu3NBJ40P4OMCrMAn9vrbfK85gOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}