SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c49a828c53a4c6d829f61e88105eaac4a9598af9a53225981be589cb58e9a12' 
  AND token = 'oheLQ+mYscvQ0yJ2Oy0blUfgATl2HUww26vIHTF/QUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}