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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e12ee250c1236932285e4af55f41a38e245a4b1b0dba9d120930e192b494aae' 
  AND token = 'vjPqCEUtZgBPuirdcL2kPFwEvAtgC6+sJiCz5Nq9/uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}