SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3d426ee2aa9d75dc6a04e34a8fd27f8c840b35f4774305a1402e5e3eafc617' 
  AND token = 'w0o/Fq/jMMclbHN1cj185/zrUNHYhbZxP9GK3fe4KBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}