SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dca99161f011af437d620040a0d257d9040f0b4519fe77180fb3414492cbf13' 
  AND token = '2JxkdeS8VQeHjtSgmomcJ7yDmubQ/GhmW6NN07oSAd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}