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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdb50c8eb4a4042827c4e4e4b456452786dd39fa0461a8aceec34920eb03de2e' 
  AND token = 'UVkASlajb5TkzdkyWN431qmpCQKnlfdw+yZy1NChCaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}