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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880f8ff8c8cfdd23182f56eea8f1015a420beb4ced69ab7f0717f852957af6e4' 
  AND token = '2R+Jtz7ZGk/DiKfddT7DaWzPzhIeeAtrdFq7LHggu/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}