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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c38bbc1b2110d6e2de2547fe6bc67806674f9b4f64a5e041105bd84f1d8faf0' 
  AND token = 'RPoaq9hrR4TrlSYcnXAj2WUfPYtzh9XZgWFw6MSaFos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}