SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f7995bec2f5b93f69b7337f63f1c0980d7aa0169c72e07dcafa2dee1bbc75cb' 
  AND token = 'ab7NmN5rgq4pKqmnIPXjQXChzSQr0rCCKMZkAvSVPk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}