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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339d9a2a100fed68854b54064e76f96435da4a504f3cbdbb28c073bbadb51776' 
  AND token = 'zuuMs6b3kHZhAv9kAv3EE4CZzG1pSKQ7ll6XUYqHS6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}