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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5648c96d3fa3fd5b9a1705ba4e15c1f1a6421dce8ac30c1eca46b3825f24c2' 
  AND token = 'f0LR2HSWXrFlV5M9cEFsBvaGJ4rdhDjdnwTUzc4v9Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}