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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49983146a3408b96d68b7b1db6375c409a151e0fc83b4d14c5e359394e44cc30' 
  AND token = 'wxr75ybhmlno90KwrWSRT5PCRUTe9hVxiZ7gb9rhGJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}