SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764b6037d8c813b26c466851f61d9b4a13106f104813856bf8c16a19258dbfae' 
  AND token = 'aP6Psk5VjRiPg2iUqPr5vnBH/GgvCp9nAFrMVLxR5DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}