SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f3361089546e94524b6615a2b126bb136c0578c0f03041a4b12c15360cbc2e' 
  AND token = 'z8j1FcUDz+8toHazP+nAqjAQo2eNbKQ9++pG/jZ+ObE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}