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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851194501530932bed6b1996012e339b61cd7f4f161ff42e8bf9f57a0dd208d3' 
  AND token = 'UMpEZ9m+uSgL8OGjx/ursnx5/xnovcYNNYzCk0Mectc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}